It happened at the intersection of Layhill Road and Bel Pre Road shortly before 2:35 p.m.
Maria Perdomo, of Silver Spring, was making a left turn from northbound Layhill Road onto westbound Bel Pre Road in a red 2013 Subaru Outback when she collided with a black 2019 Tesla Model Y that was heading southbound on Layhill Road.
Perdomo was pronounced dead at the scene, while the man driving the Tesla was taken to a nearby hospital for treatment of non-life-threatening injuries, police said.
The cause of the crash is being investigated by CRU detectives. Anyone with information is asked to call 240-773-6620.
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